This week, we were reminded of the huge strides in cancer treatment that are being made with the help of biotechnology. Two articles in the New York Times over the past few days explain how new treatments that are targeted to the specific genetic profile of a cancer are making a huge difference in patients’ lives.
From one of the articles:
For the melanoma patients who signed on to try a drug known as PLX4032, the clinical trial was a last resort. Their bodies were riddled with tumors, leaving them almost certainly just months to live.
But a few weeks after taking their first dose, nearly all of them began to recover.
Lee Reyes, 30, of Fresno, Calif., who had begun using a feeding tube because of a growth pressing against his throat, bit into a cinnamon roll.
Nothing, he told his mother, had ever tasted as good.
Rita Quigley, who had been grateful just to find herself breathing each morning since learning she had the virulent skin cancer, went shopping for new clothes with her daughters at a mall in Huntsville, Ala.
Randy Williams, 46, who drove 600 miles from his home in Jonesboro, Ark., to the M.D. Anderson Cancer Center in Houston to get the experimental drug, rolled out of bed. “Something’s working,” he thought, “because nothing’s hurting.”
It was a sweet moment, in autumn 2008, for Dr. Keith Flaherty, the University of Pennsylvania oncologist leading the drug’s first clinical trial. A new kind of cancer therapy, it was tailored to a particular genetic mutation that was driving the disease, and after six years of disappointments his faith in the promise of such a “targeted” approach finally seemed borne out. His collaborators at five other major cancer centers, melanoma clinicians who had tested dozens of potential therapies for their patients with no success, were equally elated…

2 Responses for "Biotech Responsible for Breakthrough Cancer Treatments"
THE INVESTIGATOR Dr. Keith Flaherty oversees the testing of a drug known as PLX4032 calling it the best hope against melanoma “because it is based on what makes cancer tick.”
As you can read, The research doesn’t happen over night. You need a clinical Researcher that believes in the science.
I myself, believe in our approach in how to get the host’s immune system to see the Melanoma Cancer tumor cells. I have pages of Universities, Hospitals and Drugs companies following my blog at one time or another.
I even got this note from a world renowned Clinical Researher:
Dear Mr. Breitfeller,
Mike Weber was kind to forward your paper and email. It appears that you have a very good sense of, and interest in, the immune response to melanoma and to cancer in general. I believe you are right that timing of the various components of the immune response, especially with combination therapies, is important, just as it is in the orchestration of a beautiful symphony. I wish you success in your treatments and in your work to understand and to explain the immune response to cancer.
Craig Slingluff
Craig L. Slingluff, Jr. M.D.
Joseph Helms Farrow Professor of Surgery
Division of Surgical Oncology
Vice-Chair for Research
Director, Human Immune Therapy Center
University of Virginia
I have seen this treatment work. Until we have a Clinical trial in place, we won’t know what the response rate would be.
We need more Clinical Researchers and Oncologists willing to step and think outside the box. Follow their passion and gut feelings to persue a CURE. I tip my Hat to Dr. Keith Flaherty. Thanks for thinking outside the box.
Melanoma and The Magic Bullet (Monoclonal Antibodies)
Take care
Jimmy B
Melanoma_Missionary
“Today might be the worst day of your life…but tomorrow could be the best. You just have to get there.”
~Unknown~
wow.Amazing really I dream to be involved in the next treatment
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